In first two-decade of the 21st century, there were fundamental changes that successfully transposed social world order and disposition. Even with new opportunities, technological development has also brought brand new challenges. Unfortunately, before the digital technology challenges were solved properly, the COVID-19 pandemic came across and brought other challenges to the world. Moreover, considering the COVID-19 pandemic countermeasures done almost all over the world, it is also necessary to think about and prepare for the post-pandemic digital social life condition. Accordingly, iCOMICOS 2022 will address well-being and its relatedness with technological development and culture as the foundations.